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Mar Valés-Gómez Selected Research

NK Cell Lectin-Like Receptor Subfamily K

1/2024Elevated levels of cell-free NKG2D-ligands modulate NKG2D surface expression and compromise NK cell function in severe COVID-19 disease.
1/2023NKG2D-CAR memory T cells target pediatric T-cell acute lymphoblastic leukemia in vitro and in vivo but fail to eliminate leukemia initiating cells.
5/2018Immunoassays for scarce tumour-antigens in exosomes: detection of the human NKG2D-Ligand, MICA, in tetraspanin-containing nanovesicles from melanoma.
1/2016Glycosyl-Phosphatidyl-Inositol (GPI)-Anchors and Metalloproteases: Their Roles in the Regulation of Exosome Composition and NKG2D-Mediated Immune Recognition.
8/2014Altered microRNA expression after infection with human cytomegalovirus leads to TIMP3 downregulation and increased shedding of metalloprotease substrates, including MICA.
1/2012Human NKG2D-ligands: cell biology strategies to ensure immune recognition.
1/2010Natural killer cell cytotoxicity is suppressed by exposure to the human NKG2D ligand MICA*008 that is shed by tumor cells in exosomes.
3/2008Selective induction of expression of a ligand for the NKG2D receptor by proteasome inhibitors.

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Mar Valés-Gómez Research Topics

Disease

17Neoplasms (Cancer)
10/2023 - 03/2008
7Urinary Bladder Neoplasms (Bladder Cancer)
10/2023 - 01/2015
4Non-Muscle Invasive Bladder Neoplasms
01/2023 - 01/2017
4Melanoma (Melanoma, Malignant)
01/2022 - 01/2018
4Infections
11/2021 - 08/2014
3COVID-19
01/2022 - 12/2020
2Critical Illness (Critically Ill)
01/2024 - 01/2024
2Carcinoma (Carcinomatosis)
01/2019 - 01/2015
1Asymptomatic Infections
01/2024
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2023
1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
01/2023
1Leukemia
01/2023
1Lung Neoplasms (Lung Cancer)
02/2022
1Uniparental Disomy
01/2018
1Virus Diseases (Viral Diseases)
12/2017
1Lymphopenia (Lymphocytopenia)
01/2017
1Carcinoma in Situ
01/2015
1Hematologic Neoplasms (Hematological Malignancy)
03/2008

Drug/Important Bio-Agent (IBA)

13LigandsIBA
01/2024 - 03/2008
8NK Cell Lectin-Like Receptor Subfamily KIBA
01/2024 - 03/2008
5Proteins (Proteins, Gene)FDA Link
01/2022 - 05/2018
5micaIBA
01/2021 - 01/2010
4AntigensIBA
01/2024 - 05/2018
4CytokinesIBA
01/2023 - 01/2017
4Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2019
2AntibodiesIBA
01/2024 - 11/2021
2Epithelial Cell Adhesion MoleculeIBA
02/2022 - 01/2019
2TetraspaninsIBA
01/2021 - 05/2018
2ChemokinesIBA
07/2019 - 01/2017
1Fc Receptors (Fc Receptor)IBA
01/2024
1SARS-CoV-2 membrane proteinIBA
01/2024
1Immune Checkpoint InhibitorsIBA
10/2023
1Tuberculosis VaccinesIBA
01/2023
1Chimeric Antigen ReceptorsIBA
01/2023
1Melanoma-Specific AntigensIBA
01/2022
1Viral AntigensIBA
11/2021
1Interleukin-15 (Interleukin 15)IBA
01/2021
1Neoplasm Antigens (Tumor Antigens)IBA
01/2021
1Complement System Proteins (Complement)IBA
01/2021
1Immunoglobulins (Immunoglobulin)IBA
01/2021
1Natural Killer Cell ReceptorsIBA
01/2021
1Immunoglobulin M (IgM)IBA
12/2020
1Monoclonal AntibodiesIBA
12/2020
1Peptide Hydrolases (Proteases)FDA Link
12/2020
1Immunoglobulin A (IgA)IBA
12/2020
1Immunoglobulin G (IgG)IBA
12/2020
1Chemotactic FactorsIBA
07/2019
1EpitopesIBA
05/2018
1Interferon Regulatory FactorsIBA
01/2018
1NectinsIBA
01/2018
1VemurafenibIBA
01/2018
1Histone Deacetylases (Histone Deacetylase)IBA
01/2018
1Butyric Acid (Butanoic Acid)IBA
01/2018
1Histone Deacetylase InhibitorsIBA
01/2018
1InterferonsIBA
12/2017
1Pattern Recognition ReceptorsIBA
12/2017
1Carrier Proteins (Binding Protein)IBA
12/2017
1Double-Stranded RNA (RNA, Double Stranded)IBA
12/2017
1Mitomycin (Mitomycin-C)FDA LinkGeneric
01/2017
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2017
1Metalloproteases (Metalloproteinases)IBA
08/2014
1MicroRNAs (MicroRNA)IBA
08/2014
1Proteasome InhibitorsIBA
03/2008

Therapy/Procedure

6Therapeutics
01/2021 - 03/2008
4Immunotherapy
10/2023 - 01/2017
3Intravesical Administration
10/2023 - 01/2015